I have had lots of knee problems with my left knee over the years. I think it used to be runners knee, but now I think it must be arthritis. I like cycling for getting about, but I prefer running for fitness because it's quicker. I might have to give up running, which depresses me. I've had lots of physio in the past, but that only fixes it temporarily. I've tried barefoot running shoes, motion control trainiers, and custom made othotics. None worked. I've tried seeing a chiropractors and podiatrists. I have not seen an osteopath yet. I've tried glucosamine and anti-inflamatories, didn't work neither.